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| Cat. No.: | ANXA3-1834H |
| Product Overview: | Recombinant human ANXA3 was expressed inE.coliand purified by using conventional chromatography techniques. MW = 36.3 kDa (323aa). |
| Description: | Annexin A3, also known as ANXA3, belong to the calcium dependent phospholipid binding protein family which play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1, 2 cyclic phosphates to form inositol 1 phosphate. It has been reported for the signaling cascade in rat liver regeneration. |
| Source: | E.coli. |
| Form: | Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 1mM DTT, 10% glycerol. |
| Purity: | > 90% by SDS – PAGE. |
| Concentration: | 1 mg/ml (determined by Bradford assay). |
| Sequences Of Amino Acids: | MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTPPAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEFTLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD. |
| Storage: | can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name: | ANXA3 annexin A3 [ Homo sapiens ] |
| Synonyms: | annexin A3; ANX3; ANXA3; PAP-III; annexin-3; lipocortin III; 35-alpha calcimedin; calcimedin 35-alpha; Annexin III (lipocortin III); placental anticoagulant protein III; inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha);Placental anticoagulant protein III; Lipocortin III; Annexin-3; Annexin III |
| Gene ID: | 306 |
| mRNA Refseq: | NM_005139 |
| Protein Refseq: | NP_005130 |
| MIM: | 106490 |
| UniProt ID: | P12429 |
| Chromosome Location: | 4q13-q22 |
| Function: | calcium ion binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity |
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