Recombinant Human Annexin A3

• Cat.No.: ANXA3-1834H
• Product Overview: Recombinant human ANXA3 was expressed inE.coliand purified by using conventional chromatography techniques. MW = 36.3 kDa (323aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Annexin A3, also known as ANXA3, belong to the calcium dependent phospholipid binding protein family which play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1, 2 cyclic phosphates to form inositol 1 phosphate. It has been reported for the signaling cascade in rat liver regeneration.
• Form: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 1mM DTT, 10% glycerol.
• Purity: > 90% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTPPAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEFTLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ANXA3 annexin A3 [ Homo sapiens ]
• Synonyms: annexin A3; ANX3; ANXA3; PAP-III; annexin-3; lipocortin III; 35-alpha calcimedin; calcimedin 35-alpha; Annexin III (lipocortin III); placental anticoagulant protein III; inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha);Placental anticoagulant protein III; Lipocortin III; Annexin-3; Annexin III
• Gene ID: 306
• mRNA Refseq: NM_005139
• Protein Refseq: NP_005130
• MIM: 106490
• UniProt ID: P12429
• Chromosome Location: 4q13-q22
• Function: calcium ion binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity

Citation

Fluorescent Lipo-Beads for the Sensitive Detection of Phospholipase A 2 and Its Inhibitors.

Journal: ACS biomaterials science & engineering    PubMed ID: 33455318    Data: 2021/5/14

Authors: Shahriare Hossain, Kalika R Pai, Menake E Piyasena

Article Snippet:Hydrogen peroxide (30%) was purchased from VWR (Radnor, PA).Hydrogen peroxide (30%) was purchased from VWR (Radnor, PA).. Recombinant human annexin A3 (ANXA-3) was purchased from Creative BioMart (Shirley, NY) and Abcam (Cambridge, MA).. Preparation of Fluorescent Lipo-Beads.Preparation of Fluorescent Lipo-Beads.