Recombinant Human Annexin A3 ANXA3-1834H

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Recombinant Human Annexin A3

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Cat. No. :	ANXA3-1834H
Product Overview :	Recombinant human ANXA3 was expressed inE.coliand purified by using conventional chromatography techniques. MW = 36.3 kDa (323aa).
Description :	Annexin A3, also known as ANXA3, belong to the calcium dependent phospholipid binding protein family which play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1, 2 cyclic phosphates to form inositol 1 phosphate. It has been reported for the signaling cascade in rat liver regeneration.
Source :	E.coli.
Form :	Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 1mM DTT, 10% glycerol.
Purity :	> 90% by SDS – PAGE.
Concentration :	1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids :	MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN AQRQLIVKEY QAAYGKELKD DLKGDLSGHF EHLMVALVTPPAVFDAKQLK KSMKGAGTNE DALIEILTTR TSRQMKDISQ AYYTVYKKSL GDDISSETSG DFRKALLTLA DGRRDESLKV DEHLAKQDAQILYKAGENRW GTDEDKFTEI LCLRSFPQLK LTFDEYRNIS QKDIVDSIKG ELSGHFEDLL LAIVNCVRNT PAFLAERLHR ALKGIGTDEFTLNRIMVSRS EIDLLDIRTE FKKHYGYSLY SAIKSDTSGD YEITLLKICG GDD.
Storage :	can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDB rendering based on 1aii :

Gene Name :	ANXA3 annexin A3 [ Homo sapiens ]
Synonyms :	annexin A3; ANX3; ANXA3; PAP-III; annexin-3; lipocortin III; 35-alpha calcimedin; calcimedin 35-alpha; Annexin III (lipocortin III); placental anticoagulant protein III; inositol 1,2-cyclic phosphate 2-phosphohydrolase; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha);Placental anticoagulant protein III; Lipocortin III; Annexin-3; Annexin III
Gene ID :	306
mRNA Refseq :	NM_005139
Protein Refseq :	NP_005130
MIM :	106490
UniProt ID :	P12429
Chromosome Location :	4q13-q22
Function :	calcium ion binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity