Recombinant Equine GM-CSF
Cat.No. : | GM-CSF-368E |
Product Overview : | Recombinant Equine GM-CSF was expressed inYeast.MW= 15.2 kDa (135 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | GM-CSF-368E |
Description : | GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
Source : | Yeast. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | APTRQPSPVT RPWQHVDAIK EALSLLNNSS DTAAIMNETV EVVSETFDAE ELTCLQTRLK LYKQGLRGSL IKLEGPLTMM ASHYKQHCPP TLETSCATQM ITFKSFKKNL KDFLFEIPFD CWSQPRSKAG LPARS. |
Bioactivity : | In testing. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name : | GM-CSF granulocyte-macrophage colony-stimulating-factor [ Equus caballus ] |
Synonyms : | granulocyte-macrophage colony-stimulating-factor; GM-CSF; granulocyte-macrophage colony-stimulating factor |
Gene ID : | 100033981 |
mRNA Refseq : | NM_001081882.1 |
Protein Refseq : | NP_001075351.1 |
Chromosome Location : | 14 |
Pathway : | Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; T cell receptor signaling pathway |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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