"IL10" Related Products

Recombinant Chicken Interleukin 10

Cat. No.: IL10-246C
Product Overview: Recombinant Chicken IL-10 was expressed inYeast. MW= 18.3 kDa (154 aa).
Description: Interleukin-10 is produced by murine T-cells following their stimulation by lectins. The main source for B-cell-derived Interleukin-10 in mice is Ly-1 B-cells that express CD5 and CD11. Murine keratinocytes also produce IL10.
Source: Yeast.
Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification: Ion-exchange chromatography.
Purity: >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence: LEPTCLHFSE LLPARLRELR VKFEEIKDYF QSRDDELNIQ LLSSELLDKF KGTFGCQSVS EMLRFYTDEV LPRAMQTSTS HQQSMGDLGN MLLGLKATMR RCHRFFTCEK RSKAIKQIKE TFEKMDENGI YKAMGEFDIF INYIEEYLLM RRRK.
Bioactivity: The biological activity of recombinant chicken IL-10 was determined by measuring IFN-gamma expression by RTPCR in Concanavalin A-stimulated chicken spleen lymphocytes. Results demonstrate decreased IFN-gamma gene expression, with the addition of recombinant chicken IL-10, in a dose-dependant manner, with doses starting at 2 ng/mL.
Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name: IL10 interleukin 10 [ Gallus gallus ]
Synonyms: interleukin 10; IL-10; IL10; interleukin-10
Gene ID: 428264
mRNA Refseq: NM_001004414.2
Protein Refseq: NP_001004414.2
UniProt ID: Q6A2H4
Chromosome Location: 26
Pathway: Cytokine-cytokine receptor interaction; Intestinal immune network for IgA production; Jak-STAT signaling pathway
Function: cytokine activity; protein binding

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