Recombinant Human Beta-2-Microglobulin B2M-1905H

Recombinant Human Beta-2-Microglobulin

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human Beta-2-Microglobulin

Recombinant Human Beta-2-Microglobulin

B2M Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : B2M-1905H
Product Overview : Recombinant Human β2 Microglobulin protein was expressed in insect cells.The expressed protein was purified by a combination of ion-exchange and gel-filtration methods.
Description : The major histocompatibility complex (MHC) gene locus encodes a group of highly polymorphic, cell surface proteins that play a broad role in the immune response to protein antigens. MHC molecules function by binding and presenting small antigenic protein fragments to antigen-specific receptors expressed by T cells (TCR). Class I MHC molecules consist of two separate polypeptide chains. The class I α chain is an MHC encoded, transmembrane polypeptide containing three extracellular domains: α1, α2 and α3. The second chain consists of a non-MHC encoded, 12 kDa polypeptide called β2 microglobulin (β2M). Since β2M does not contain a transmembrane domain, it associates with the a chain through non-covalent interaction. This association is important for the stability of the MHC class I structure, its peptide-loading and its ability to present peptide antigen to CD8+ T cells. β2M is relatively invariant within each species. For example, human β2M is reported to have high affinity for human and mouse MHC class I heavy chains.
Source : Insect cells.
Amino Acid Sequence : The sequence of the first five N-terminal amino acids was determined and was found to be Lys-Ala-Met-His-Val.
Concentration : 0.5 mg/ml.
Storage Buffer : Aqueous buffered solution containing ≤0.09% sodium azide.
Preparation And Storage : Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Gene Name : B2M beta-2-microglobulin [ Homo sapiens ]
Synonyms : B2M; beta-2-microglobulin; Beta-2 microglob ulin form pI 5.3; beta-2-microglobin; beta chain of MHC class I molecules
Gene ID : 567
mRNA Refseq : NM_004048
Protein Refseq : NP_004039
MIM : 109700
UniProt ID : P61769
Chromosome Location : 15q21-q22.2
Pathway : Antigen processing and presentation; HIV Infection; Signaling in Immune system
Function : protein binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy