Recombinant Human Collagen, Type III, Alpha 1


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Recombinant Human Collagen, Type III, Alpha 1

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Cat. No. : COL3A1-1957H
Product Overview : Recombinant Human collagen-III encoding proalpha (III) and both alpha and beta subunits of the prolyl hydoxylase were coexpressed in the yeastPichia Pastoris. Procollagen III was converted to mature collagen by controlled proteinase digestion.
Description : Collagen, a major component of the extracellular matrix, is a fibrous protein that provides tensile strength to tissues giving them structural integrity. Collagen and its derivative, gelatin, have been widely used in medical, pharmaceutical and consumer products for more than 100 years. Products that contain animal-derived collagen can induce potentially harmful inflammatory or immune responses in humans and pose risk of contamination with viruses or prions, potentially life-threatening pathogens. Recombinant collagens are essentially identical to the native collagen protein thereby reducing the risk of inflammation, immune response, and disease as compared to animal-sourced collagen.
Source : Pichia Pastoria.
Physical Appearance : Sterile filtered liquid.
Purity : ≥95% as determined by SDS-PAGE.
Formulation : 3.5 mg/ml in 10 mM HCl.
Storage Conditions : Recombinant Human Collagenase-III should be stored at 2-8°C.
Gene Name : COL3A1 collagen, type III, alpha 1 [ Homo sapiens ]
Synonyms : collagen, type III, alpha 1; EDS4A; FLJ34534; COL3A1; collagen alpha-1(III) chain; collagen, fetal; alpha1 (III) collagen; Ehlers-Danlos syndrome type IV, autosomal dominant; collagen type III alpha 1
Gene ID : 1281
mRNA Refseq : NM_000090.3
Protein Refseq : NP_000081.1
MIM : 120180
UniProt ID : P02461
Chromosome Location : 2q31
Pathway : ECM-receptor interaction; Focal adhesion; Axon guidance; Signaling by PDGF
Function : SMAD binding; extracellular matrix structural constituent; integrin binding; platelet-derived growth factor binding; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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