Recombinant Rat Fibroblast Growth Factor 7 Fgf7-372R

Recombinant Rat Fibroblast Growth Factor 7

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Recombinant Rat Fibroblast Growth Factor 7

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Cat. No. : Fgf7-372R
Product Overview : Recombinant Rat Fibroblast Growth Factor 7 was expressed inE.Coli.MW=17 kDa.
Description : Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.
Source : E. coli.
Purity : Purity > 90%. Purified by heparin affinity chromatography.
Activity : The activity of rat FGF-7 at 1-10 ng/ml is determined by tritiated thymidine incorporation using cultured mouse keratinocytes. Maximum stimulation observed at 1 ng/ml. The optimal concentration of this product for use with other cell types must be determined by the end user.
Specifity : 45102 binds to keratinocytes and most parenchymal epithelial cells; binds specific splice variant of FGF receptor expessed in epithelial cells (FGFr2IIIb).
Content : Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm. 2. Analysis by RP-HPLC, using a calibrated solution of IGF-II as a Reference Standard.
Storage : This product is stable for at least one year at -20℃ to -70℃. Keep frozen until use. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Gene Name : Fgf7 fibroblast growth factor 7 [ Rattus norvegicus ]
Synonyms : Fgf7; fibroblast growth factor 7; Kgf; fibroblast growth factor 7; FGF-7; HBGF-7; keratinocyte growth factor; heparin-binding growth factor 7
Gene ID : 29348
mRNA Refseq : NM_022182
Protein Refseq : NP_071518
UniProt ID : Q02195
Chromosome Location : 3q36
Pathway : MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton
Function : chemoattractant activity; growth factor activity; heparin binding; protein binding; type 2 fibroblast growth factor receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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