"SEMA6B" Related Products

Recombinant Human SEMA6B, Fc Chimera

Cat. No. : SEMA6B-1925H
Product Overview : Recombinant Human SEMA6B fussed with a Fc region of human IgG1 at the C-terminus via a peptide linker was expressed in a mouse myeloma cell line,NS0.
Description : This gene encodes a member of the semaphorin family, a group of proteins characterized by the presence of a conserved semaphorin (sema) domain. Whereas some semaphorins are transmembrane proteins, others are secreted. Semaphorins play a major role in axon guidance. The protein encoded by this gene may be involved in both peripheral and central nervous system development.
Source : NS0.
Purity : > 95%, as determined by SDS-PAGE and visualized by silver stain.
Molecular Mass : The mature recombinant human Semaphprin 6B/Fc chimera, generated by proteolytic removal of the signal peptide region, is a homodimeric protein. Based on N-terminal sequencing, the mature recombinant human Semaphorin 6B protein starts at Leu 26. The monomer of the recombinant human Semaphorin 6B has a calculated molecular mass of approximately 63.4 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 - 120 kDa protein in SDS-PAGE under reducing conditions.
Activity : Measured by its ability to cause collapse of chick DRG growth cones. The ED50 for this effect is typically 2.5 - 5.0 μg/mL in the presence of 10 ng/mL of rhβ-NGF.
Endotoxin : < 1.0 EU per 1 μg of the enzyme as determined by the LAL method.
Format : Lyophilized from a 0.2 μm filtered solution in PBS.
Storage : Samples are stable for up to six months at -70°C in a manual defrost freezer after the date of receipt. After receiving, this protein can be aliquoted and stored at above temperature for up to six months without a significant loss of activity. Avoid repeated freeze-thaw cycles.
Gene Name : SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B [ Homo sapiens ]
Synonyms : SEMA6B; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B; SEMAN; semaZ; SEMA-VIB; SEM-SEMA-Y; SEMA6B; semaphorin Z; semaphorin VIB
Gene ID : 10501
mRNA Refseq : NM_032108
Protein Refseq : NP_115484
MIM : 608873
UniProt ID : Q9H3T3
Chromosome Location : 19p13
Function : protein binding; protein binding; protein complex binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.