Recombinant Human Deoxynucleotidyltransferase, Terminal
| Cat.No. : |
DNTT-563H |
| Product Overview : |
Recombinant Human Deoxynucleotidyltransferase, Terminal encoding 1-200 amino acids expressed inE.coli. The TDT is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
| Cat. No. : |
DNTT-563H |
| Description : |
Terminal Deoxynucleotidyl Transferase (TdT). TdT is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3-hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemias. The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt‘s lymphoma. |
| Source : |
Escherichia Coli. |
| Physical Appearance : |
Sterile filtered liquid. |
| Formulation : |
TDT protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
| Stability : |
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles. Application And Suggested Dilutions: 1. ELISA 2. Inhibition Assays 3. Western Blotting Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 50 kDa. |
| Gene Name : |
DNTT deoxynucleotidyltransferase, terminal [ Homo sapiens ] |
| Synonyms : |
DNTT; deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; terminal addition enzyme; terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; terminal transferase; TDT; EC 2.7.7.31 |
| Gene ID : |
1791 |
| mRNA Refseq : |
NM_001017520 |
| Protein Refseq : |
NP_001017520 |
| MIM : |
187410 |
| UniProt ID : |
P04053 |
| Chromosome Location : |
10q23-q24 |
| Pathway : |
Hematopoietic cell lineage; Non-homologous end-joining |
| Function : |
DNA binding; DNA nucleotidylexotransferase activity; DNA-directed DNA polymerase activity; metal ion binding; transferase activity |
Products Types
Related Gene
DNTT
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
