Recombinant Human Arachidonate 5-lipoxygenase 1

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Recombinant Human Arachidonate 5-lipoxygenase 1

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Cat. No. : ALOX5-578H.
Product Overview : Recombinant Human Arachidonate 5-lipoxygenase 1 is expressed ina Baculovirus overexpression system inSf21 cells. The molecular weight of the recombinant ALOX5 is 78 kDa.
Description : Arachidonate 5-lipoxygenase (5-lipoxygenase, 5-LO or Alox5) is a member of the lipoxygenase family of enzymes. It transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid.
Source : Sf21 cells.
Purity : cell lysate 16,000 x g supernatant.
Formulation : A solution in 100 mM Tris, pH 8.0, containing 2 mM EGTA.
Storage : -80℃, 6 months.
Gene Name : ALOX5 arachidonate 5-lipoxygenase [ Homo sapiens ]
Synonyms : arachidonate 5-lipoxygenase; ALOX5; 5-LO; 5LPG; LOG5; 5-LOX; MGC163204; leukotriene A4 synthase; arachidonic acid 5-lipoxygenase
Gene ID : 240
mRNA Refseq : NM_000698
Protein Refseq : NP_000689
MIM : 152390
UniProt ID : P09917
Chromosome Location : 8p12
Pathway : Arachidonic acid metabolism; Metabolic pathwaysy
Function : arachidonate 5-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity;protein binding

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