Recombinant Human BMX Non-receptor Tyrosine Kinase, Active
Cat.No. : | BMX-654H |
- Specification
- Gene Information
- Related Products
Cat. No. : | BMX-654H |
Description : | The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX, is found to induce activation of the Stat signaling pathway. |
Source : | Escherichia coli. |
Biochem/physiol Actions : | The BMX gene encodes a novel non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. Bmx induces the activation of the Stat-signaling pathway. |
Unit Definition : | Kinase activity is measured as the molar amount of phosphate incorporated into Poly Glu-Tyr substrate per minute per mg protein at 30 °C using a final concentration of 50 μM [32P]-ATP. |
Physical Form : | Solution of 50 μL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol. |
Assay : | ≥85% (SDS-PAGE). |
Form : | buffered aqueous glycerol solution. |
Mol Wt : | apparent mol wt ~110 kDa. |
Storage Temp : | −70°C. |
Pathways : | Apoptosis |
Gene Name : | BMX BMX non-receptor tyrosine kinase [ Homo sapiens ] |
Synonyms : | BMX non-receptor tyrosine kinase; ETK; PSCTK2; PSCTK3; BMX; OTTHUMP00000022965; NTK38 tyrosine kinase; Etk/Bmx cytosolic tyrosine kinase; cytoplasmic tyrosine-protein kinase BMX; EC 2.7.10.2; NTK38; OTTHUMP00000022964; OTTHUMP00000022966; Epithelial and endothelial tyrosine kinase; Bone marrow tyrosine kinase gene in chromosome X protein |
Gene ID : | 660 |
mRNA Refseq : | NM_001721 |
Protein Refseq : | NP_001712 |
MIM : | 300101 |
UniProt ID : | P51813 |
Chromosome Location : | Xp22.2 |
Function : | non-membrane spanning protein tyrosine kinase activity; ATP binding; metal ion binding; nucleotide binding; protein binding; signal transducer activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
Bmx-716M | Recombinant Mouse Bmx Protein, MYC/DDK-tagged | +Inquiry |
BMX-452H | Recombinant Human BMX Protein, His (Fc)-Avi-tagged | +Inquiry |
BMX-0752H | Recombinant Human BMX Protein (E411-H675), His tagged | +Inquiry |
BMX-0751H | Recombinant Human BMX Protein (E411-H675), Tag Free | +Inquiry |
BMX-290H | Recombinant Human BMX Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BMX-8427HCL | Recombinant Human BMX 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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