Recombinant Human SIRT7, His-tagged
Cat.No. : | SIRT7-585H |
Product Overview : | Full length (2-400aa) recombinant Human SIRT7 expressed inE.coliN-terminal was fused to his-tagged SIRT7. MW = 49.3 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SIRT7-585H |
Description : | The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-SIRT7. Recently, SIRT7 has been shown to activate transcription of RNA polymerase I and deacetylate p53. SIRT7 prevents progressive functional deterioration of the heart, and is suggested to play an important role in regulation of stress responses and cell death in the heart. |
Source : | E.coli. |
Purity : | ≥85%. |
Formulation : | 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride, 5 mM DTT, and 20% glycerol. |
Stability : | ≥6 months at -80°C; avoid freeze/thaw cycles by aliquoting the protein and storing at -80°C. |
Gene Name : | SIRT7 sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) [ Homo sapiens ] |
Synonyms : | SIRT7; sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae); SIR2L7; MGC126840; MGC126842; NAD-dependent deacetylase sirtuin-7; sirtuin type 7; SIR2-like protein 7; sir2-related protein type 7; silent mating type information regulation 2, S.cerevisiae, homolog 7; EC 3.5.1.-; sirtuin 7 |
Gene ID : | 51547 |
mRNA Refseq : | NM_016538 |
Protein Refseq : | NP_057622 |
MIM : | 606212 |
UniProt ID : | Q9NRC8 |
Chromosome Location : | 17q25 |
Function : | NAD binding; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; metal ion binding; protein binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
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SIRT7-5069R | Recombinant Rat SIRT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
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SIRT7-4023R | Recombinant Rhesus Macaque SIRT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIRT7-1828HCL | Recombinant Human SIRT7 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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