Recombinant Mouse Tnfsf4, FLAG-tagged
Cat.No. : | Tnfsf4-2074M |
Product Overview : | Recombinant Mouse Tnfsf4 is produced inHEK 293 Cells. The extracellular domain of mouse CD134L (OX40L) (aa 52-198) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG-tag. MW=28kDa. |
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- Gene Information
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Cat. No. : | Tnfsf4-2074M |
Description : | OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252 (cluster of differentiation 252). |
Source : | HEK 293 Cells. |
Purity : | ≥90% (SDS-PAGE). |
Concentration : | 0.1mg/ml after reconstitution. |
Formulation : | Lyophilized. Contains PBS. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 100µl sterile water. |
Specificity : | Binds to human and mouse CD134 (OX40). |
Biological Activity : | Activates T cell proliferation. |
Storage : | -20°C. |
Gene Name : | Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 [ Mus musculus ] |
Synonyms : | Tnfsf4; tumor necrosis factor (ligand) superfamily, member 4; Ath1; gp34; Ath-1; Ox40l; TXGP1; CD134L; OX-40L; Txgp1l; Tnfsf4; tumor necrosis factor ligand superfamily member 4; OX40 ligand; atherosclerosis 1; tax-transcriptionally activated glycoprotein 1 ligand |
Gene ID : | 22164 |
mRNA Refseq : | NM_009452 |
Protein Refseq : | NP_033478 |
UniProt ID : | P43488 |
Chromosome Location : | 1 H2.1; 1 84.9 cM |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic changes in TNFSF4 affect immune regulation and autoimmune disease susceptibility.
TNFSF4 (OX40L) regulates immune responses and T-cell activation.
It activates T-cells, stimulating inflammatory cytokine production.
TNFSF4 is implicated in autoimmune disease development by promoting immune cell activation.
TNFSF4 interacts with OX40 and other receptors, influencing immune signaling.
Targeting TNFSF4 could treat autoimmune and inflammatory diseases by modulating the immune system.
Altered TNFSF4 activity contributes to chronic inflammation.
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