Active Recombinant Human FURIN Protein

• Cat.No.: FURIN-605H
• Product Overview: Recombinant human FURIN (aa 108-714) protein does not contain the C-terminal and transmembrane domains was produced in Drosophila melanogaster Schneider 2 cells.

Specification

• Source: Drosophila melanogaster Schneider 2 cells
• Species: Human
• Form: Liquid
• Bio-activity: Cleaves precursor proteins C-terminal to an Arg-X-X-Arg motif.
  Specific Activity: One unit cleaves 24pmol (2µg) of protective antigen or 100pmol (2.5µg) of human proendothelin-1 per hour at 30centigrade in 100mM HEPES, pH 7.6, containing 1mM calcium dichloride, 0.5% Triton X-100 and 1mM 2-mercaptoethanol.
• Molecular Mass: ~81kDa
• Purity: ≥90% (one major band at ≥83kDa)
• Notes: For Research Use Only, Not for Human.
• Stability: Do not aliquot. Keep vial on ice during use and put immediately back in -80 centigrade freezer.
• Storage: At -80 centigrade. Do not freeze/thaw.
• Concentration: 1U/µl
• Storage Buffer: In 100mM HEPES, pH 7.5, containing 25% glycerol, 150mM sodium chloride and 1mM calcium dichloride.

Gene Information

• Gene Name: FURIN
• Official Symbol: FURIN furin, paired basic amino acid cleaving enzyme [ Homo sapiens (human) ]
• Synonyms: FURIN; furin, paired basic amino acid cleaving enzyme; FUR; PACE; SPC1; PCSK3
• Gene ID: 5045
• mRNA Refseq: NM_002569
• Protein Refseq: NP_002560
• MIM: 136950
• UniProt ID: P09958