Recombinant Human Deoxyribonuclease I-like 3

• Cat.No.: DNASE1L3-622H
• Product Overview: Recombinant Human Deoxyribonuclease I-like 3 is produced inE. coli.

Specification

• Cat. No.: DNASE1L3-622H
• Description: Deoxyribonuclease gamma is an enzyme that in humans is encoded by the DNASE1L3 gene. This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
• Source: E. coli.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Liquid. In 25mM TRIS-HCl, pH 7.5, containing 150mM potassium chloride and 50% glycerol.
• Application: For studying DNAS1L3 catalyzed oligonucleosomal DNA fragmentation.
• Storage And Stability: Stable for at least 6 months after receipt when stored at -80°C.

Gene Information

• Gene Name: DNASE1L3 deoxyribonuclease I-like 3 [ Homo sapiens ]
• Synonyms: DNASE1L3; deoxyribonuclease I-like 3; DNase I homolog protein 2; DNase I homolog protein DHP2; DNase I-like 3; DNase gamma; LS-DNase; Liver and spleen DNase; deoxyribonuclease I-like III; deoxyribonuclease gamma; DHP2, DNAS1L3; EC 3.1.21.-
• Gene ID: 1776
• mRNA Refseq: NM_004944
• Protein Refseq: NP_004935
• MIM: 602244
• UniProt ID: Q13609
• Chromosome Location: 3p21.1-p14.3
• Function: DNA binding; calcium ion binding; deoxyribonuclease activity; endodeoxyribonuclease activity; hydrolase activity