Recombinant Mouse Tnfrsf23, Fc Chimera


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Recombinant Mouse Tnfrsf23, Fc Chimera

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Cat. No. : Tnfrsf23-2111M
Product Overview : Recombinant Mouse Tnfrsf23 was produced inHEK 293cells. The extracellular domain of mouse DcTRAIL-R1 (aa 1-160) is fused to the Fc portion of human IgG1. MW = ~52kDa (SDS-PAGE).
Source : HEK 293.
Purity : ≥90% (SDS-PAGE).
Formulation : Lyophilized. Contains PBS.
Concentration : 1mg/ml after reconstitution.
Biological Activity : Inhibits mouse soluble TRAIL-induced apoptosis assessed in human Jurkat T-lymphoma cells and human B cells myeloma (BJAB) in a concentration range of 500-1'000ng/ml.
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution : Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or other carrier protein.
Specificity : rmDcTRAIL-R1:Fc binds mouse soluble TRAIL in an ELISA assay. Does not bind human soluble TRAIL.
Application : Cell surface staining of mouse TRAIL by flow cytometry in combination with PAb to human IgG.
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Gene Name : Tnfrsf23 tumor necrosis factor receptor superfamily, member 23 [ Mus musculus ]
Synonyms : Tnfrsf23; tumor necrosis factor receptor superfamily, member 23; mSOB; Tnfrh1; Dctrailr1; MGC123882; MGC123883; Tnfrsf1al1; mDcTrailr1; tumor necrosis factor receptor superfamily member 23; OTTMUSP00000028319; TNF receptor homolog 1; decoy TRAIL receptor 1; TNF receptor family member SOB; tumor necrosis factor receptor p60 homolog 1; tumor necrosis factor receptor superfamily, member 1a-like 1
Gene ID : 79201
mRNA Refseq : NM_024290
Protein Refseq : NP_077252
UniProt ID : Q9ER63
Chromosome Location : 7 F5; 7 69.56 cM
Function : protein binding; receptor activity

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