Recombinant Human Ectodysplasin A Receptor, Fc Chimera EDAR-2119H

Recombinant Human Ectodysplasin A Receptor, Fc Chimera


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Recombinant Human Ectodysplasin A Receptor, Fc Chimera

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Cat. No. : EDAR-2119H
Product Overview : Recombinant Human EDAR was produced inE. coli.The cysteine-rich region of human EDAR (ectodysplasin-A receptor) (aa 1-183) is fused to the Fc portion of human IgG1.
Description : This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Source : E. coli.
Purity : ≥95% (SDS-PAGE).
Formulation : Lyophilized. Contains PBS.
Concentration : 1mg/ml after reconstitution.
nullValue_other : Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Gene Name : EDAR ectodysplasin A receptor [ Homo sapiens ]
Synonyms : EDAR; ectodysplasin A receptor; DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; EDA-A1R; FLJ94390; tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor
Gene ID : 10913
mRNA Refseq : NM_022336
Protein Refseq : NP_071731
MIM : 604095
UniProt ID : Q9UNE0
Chromosome Location : 2q11-q13
Pathway : Cytokine-cytokine receptor interaction
Function : protein binding; receptor activity; transmembrane receptor activity

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