Recombinant Mouse C-type Lectin Domain Family 4, Member N, Fc Chimera


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Recombinant Mouse C-type Lectin Domain Family 4, Member N, Fc Chimera

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Cat. No. : Clec4n-2122M
Product Overview : Recombinant Mouse Clec4n was produced inHEK 293 cells.The extracellular domain of dectin-2 (aa 44-209) is fused at the N-terminus to the Fc portion of human IgG1. MW = ~55kDa (SDS-PAGE).
Description : Dectin-2 (dendritic cell-associated C-type lectin-2) is a lectin that has been reported to bind to zymosan as well as to hyphae of organisms such asCandida albicans. Dectin-2 exhibits specific recognition of high-mannose structures. Activation of Dectin-2 leads to phosphorylation of FcRg and up-regulated secretion of TNFα and IL-1ra. Dectin-2 might act on inflammatory macrophages and DC to detect pathogenic organisms and possibly endogenous glycoproteins.
Source : HEK 293 cells.
Purity : ≥95% (SDS-PAGE).
Concentration : 1mg/ml after reconstitution.
Formulation : Lyophilized. Contains PBS.
Reconstitution : Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Gene Name : Clec4n C-type lectin domain family 4, member n [ Mus musculus ]
Synonyms : Clec4n; C-type lectin domain family 4, member n; Nkcl; Clec6a; Clecsf10; C-type lectin domain family 6 member A; dectin-2; DC-associated C-type lectin 2; natural killer complex lectin; C-type lectin superfamily member 10; dendritic cell-associated C-type lectin 2; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10
Gene ID : 56620
mRNA Refseq : NM_020001
Protein Refseq : NP_064385
UniProt ID : Q9JKF4
Chromosome Location : 6 F3; 6 55.0 cM
Function : Binding; sugar binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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