"Clec4n" Related Products

Recombinant Mouse C-type Lectin Domain Family 4, Member N, Fc Chimera

Cat. No. : Clec4n-2122M
Product Overview : Recombinant Mouse Clec4n was produced inHEK 293 cells.The extracellular domain of dectin-2 (aa 44-209) is fused at the N-terminus to the Fc portion of human IgG1. MW = ~55kDa (SDS-PAGE).
Description : Dectin-2 (dendritic cell-associated C-type lectin-2) is a lectin that has been reported to bind to zymosan as well as to hyphae of organisms such asCandida albicans. Dectin-2 exhibits specific recognition of high-mannose structures. Activation of Dectin-2 leads to phosphorylation of FcRg and up-regulated secretion of TNFα and IL-1ra. Dectin-2 might act on inflammatory macrophages and DC to detect pathogenic organisms and possibly endogenous glycoproteins.
Source : HEK 293 cells.
Purity : ≥95% (SDS-PAGE).
Concentration : 1mg/ml after reconstitution.
Formulation : Lyophilized. Contains PBS.
Reconstitution : Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Gene Name : Clec4n C-type lectin domain family 4, member n [ Mus musculus ]
Synonyms : Clec4n; C-type lectin domain family 4, member n; Nkcl; Clec6a; Clecsf10; C-type lectin domain family 6 member A; dectin-2; DC-associated C-type lectin 2; natural killer complex lectin; C-type lectin superfamily member 10; dendritic cell-associated C-type lectin 2; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10
Gene ID : 56620
mRNA Refseq : NM_020001
Protein Refseq : NP_064385
UniProt ID : Q9JKF4
Chromosome Location : 6 F3; 6 55.0 cM
Function : Binding; sugar binding

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