|Cat. No. :
|Product Overview :
||Recombinant Mouse Clec4n was produced inHEK 293 cells.The extracellular domain of dectin-2 (aa 44-209) is fused at the N-terminus to the Fc portion of human IgG1. MW = ~55kDa (SDS-PAGE).
||Dectin-2 (dendritic cell-associated C-type lectin-2) is a lectin that has been reported to bind to zymosan as well as to hyphae of organisms such asCandida albicans. Dectin-2 exhibits specific recognition of high-mannose structures. Activation of Dectin-2 leads to phosphorylation of FcRg and up-regulated secretion of TNFα and IL-1ra. Dectin-2 might act on inflammatory macrophages and DC to detect pathogenic organisms and possibly endogenous glycoproteins.
||HEK 293 cells.
||1mg/ml after reconstitution.
||Lyophilized. Contains PBS.
||Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
|Endotoxin Content :
||<0.1EU/µg purified protein (LAL test; Bio Whittaker).
||Stable for at least 6 months after receipt when stored at -20°C.