Recombinant Human SULT2B1, His-tagged

• Cat.No.: SULT2B1-2046H
• Product Overview: Recombinant human SULT2B1, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 41.3 kDa (365aa).

Specification

• Cat. No.: SULT2B1-2046H
• Description: Sulfotransferase family cytosolic 2B member 1 isoform b, also known as SULT2B1, is a member of Sulfotransferase family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and may also have a role in cholesterol sulfation in human skin.
• Source: E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 10% glycerol.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPSWIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFLKGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRGAFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETPHPRPS.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 [ Homo sapiens ]
• Synonyms: sulfotransferase family, cytosolic, 2B, member 1; HSST2; SULT2B1; sulfotransferase family cytosolic 2B member 1; ST2B1; sulfotransferase 2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2;Hydroxysteroid sulfotransferase 2; Sulfotransferase 2B1; Alcohol sulfotransferase; EC 2.8.2.2
• Gene ID: 6820
• mRNA Refseq: NM_004605
• Protein Refseq: NP_004596
• MIM: 604125
• UniProt ID: O00204
• Chromosome Location: 19q13.3
• Pathway: Steroid hormone biosynthesis; Sulfur metabolism; Biological oxidations
• Function: alcohol sulfotransferase activity; protein binding; steroid sulfotransferase activity; transferase activity