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Recombinant Human Chromogranin B (Secretogranin 1), His-tagged

Cat. No.: CHGB-2056H
Product Overview: Recombinant human CHGB protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 78.4 kDa (677aa).
Description: CHGB, also known as secretogranin-1 or chromogranin-B, is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. This protein Belongs to the chromogranin/secretogranin protein family and is expressed in the adrenal medulla, and in pheochromocytoma.
Source: E.coli.
Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl.
Purity: > 80% by SDS - PAGE.
Concentration: 0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MPVDNRNHNE GMVTRCIIEV LSNALSKSSA PPITPECRQV LKTSRKDVKD KETTENENTK FEVRLLRDPADASEAHESSS RGEAGAPGEE DIQGPTKADT EKWAEGGGHS RERADEPQWS LYPSDSQVSE EVKTRHSEKS QREDEEEEEG ENYQKGERGEDSSEEKHLEE PGETQNAFLN ERKQASAIKK EELVARSETH AAGHSQEKTH SREKSSQESG EEAGSQENHP QESKGQPRSQ EESEEGEEDATSEVDKRRTR PRHHHGRSRP DRSSQGGSLP SEEKGHPQEE SEESNVSMAS LGEKRDHHST HYRASEEEPE YGEEIKGYPG VQAPEDLEWERYRGRGSEEY RAPRPQSEES WDEEDKRNYP SLELDKMAHG YGEESEEERG LEPGKGRHHR GRGGEPRAYF MSDTREEKRF LGEG HHRVQENQMDKARRHP QGAWKELDRN YLNYGEEGAP GKWQQQGDLQ DTKE NREEAR FQDKQYSSHH TAEKRKRLGE LFNPYYDPLQ WKSSHFERRD NMND NFLEGE EENELTLNEK NFFPEYNYDW WEKKPFSEDV NWGYEKRNLA RVPKL DLKRQ YDRVAQLDQL LHYRKKSAEF PDFYDSEEPVSTHQEAENEK DRAD QTVLTE DEKKELENLA AMDLELQKIA EKFSQRG.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CHGB chromogranin B (secretogranin 1) [ Homo sapiens ]
Synonyms: chromogranin B (secretogranin 1); SCG1; CHGB; secretogranin-1; cgB; sgI; chromogranin-B; secretogranin B; secretogranin I;Secretogranin I; SgI; CgB; Chromogranin-B
Gene ID: 1114
mRNA Refseq: NM_001819
Protein Refseq: NP_001810
MIM: 118920
UniProt ID: P05060
Chromosome Location: 20pter-p12
Function: hormone activity; protein binding

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