Recombinant Human Chromogranin B (Secretogranin 1), His-tagged

• Cat.No.: CHGB-2056H
• Product Overview: Recombinant human CHGB protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 78.4 kDa (677aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CHGB, also known as secretogranin-1 or chromogranin-B, is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. This protein Belongs to the chromogranin/secretogranin protein family and is expressed in the adrenal medulla, and in pheochromocytoma.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl.
• Purity: > 80% by SDS - PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MPVDNRNHNE GMVTRCIIEV LSNALSKSSA PPITPECRQV LKTSRKDVKD KETTENENTK FEVRLLRDPADASEAHESSS RGEAGAPGEE DIQGPTKADT EKWAEGGGHS RERADEPQWS LYPSDSQVSE EVKTRHSEKS QREDEEEEEG ENYQKGERGEDSSEEKHLEE PGETQNAFLN ERKQASAIKK EELVARSETH AAGHSQEKTH SREKSSQESG EEAGSQENHP QESKGQPRSQ EESEEGEEDATSEVDKRRTR PRHHHGRSRP DRSSQGGSLP SEEKGHPQEE SEESNVSMAS LGEKRDHHST HYRASEEEPE YGEEIKGYPG VQAPEDLEWERYRGRGSEEY RAPRPQSEES WDEEDKRNYP SLELDKMAHG YGEESEEERG LEPGKGRHHR GRGGEPRAYF MSDTREEKRF LGEG HHRVQENQMDKARRHP QGAWKELDRN YLNYGEEGAP GKWQQQGDLQ DTKE NREEAR FQDKQYSSHH TAEKRKRLGE LFNPYYDPLQ WKSSHFERRD NMND NFLEGE EENELTLNEK NFFPEYNYDW WEKKPFSEDV NWGYEKRNLA RVPKL DLKRQ YDRVAQLDQL LHYRKKSAEF PDFYDSEEPVSTHQEAENEK DRAD QTVLTE DEKKELENLA AMDLELQKIA EKFSQRG.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CHGB chromogranin B (secretogranin 1) [ Homo sapiens ]
• Synonyms: chromogranin B (secretogranin 1); SCG1; CHGB; secretogranin-1; cgB; sgI; chromogranin-B; secretogranin B; secretogranin I;Secretogranin I; SgI; CgB; Chromogranin-B
• Gene ID: 1114
• mRNA Refseq: NM_001819
• Protein Refseq: NP_001810
• MIM: 118920
• UniProt ID: P05060
• Chromosome Location: 20pter-p12
• Function: hormone activity; protein binding