Recombinant Mouse Toll-like Receptor 6, Fc Chimera

• Cat.No.: Tlr6-2433M
• Product Overview: Recombinant extracellular domain of mouse TLR6 (aa 24-594) produced inHEK 293 cellsis fused at the C-terminus to the Fc portion of human IgG1 and a linker peptide (10 aa). 140kDa (SDS-PAGE).

Specification

• Cat. No.: Tlr6-2433M
• Description: Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene.TLR6 has also been designated as CD286 (cluster of differentiation 286). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity.
• Source/Host: HEK 293 cells.
• Concentration: 1mg/ml after reconstitution.
• Purity: >90% (SDS-PAGE).
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
• Formulation: Lyophilized. Contains PBS.
• Long Term Storage: -20°C.
• Use/Stability: Stable for at least 6 months after receipt when stored at -20°C.
• Handling: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Tlr6 toll-like receptor 6 [ Mus musculus ]
• Synonyms: toll-like receptor 6; Tlr6
• Gene ID: 21899
• mRNA Refseq: NM_011604
• Protein Refseq: NP_035734
• UniProt ID: Q9EPW9
• Chromosome Location: 5 C3.1; 5 37.0 cM
• Pathway: Chagas disease; Toll-like receptor signaling pathway
• Function: diacylated lipopeptide binding; lipoprotein binding; protein binding; protein heterodimerization activity; receptor activity; transmembrane receptor activity