Recombinant Human FYN, GST-tagged
Cat.No. : | FYN-2410H |
Product Overview : | Recombinant Human FYN p59 (23-216aa) was expressed inE. coli.It was fused with a GST tag at the N-terminus. |
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Cat. No. : | FYN-2410H |
Description : | p59fyn is a membrane-associated non-receptor protein tyrosine kinase that belongs to the Src-family of kinases. The unique N-terminal domain of p59fyn interacts with the CD3 and eta chains of the TcR. p59fyn can bind other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of fyn activity. p59fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation. |
Source : | E. coli. |
Presentation : | 100μl purified human Lyn protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide. |
Applications : | ELISA•Inhibition Assays• Western Blotting. |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 50 kDa (including GST). |
Storage & Stability : | Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. |
Gene Name : | FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ] |
Synonyms : | FYN oncogene related to SRC, FGR, YES; SLK; SYN; MGC45350; FYN; proto-oncogene tyrosine-protein kinase fyn; src-like kinase; Protooncogene Syn; OTTHUMP00000017917; c-syn protooncogene; src/yes-related novel; tyrosine kinase p59fyn(T); p59-Fyn; protein-tyrosine kinase fyn ; OKT3-induced calcium influx regulator; EC 2.7.10.2; OTTHUMP00000017915; OTTHUMP00000017914; src-like kinase |
Gene ID : | 2534 |
mRNA Refseq : | NM_002037 |
Protein Refseq : | NP_002028 |
UniProt ID : | P06241 |
Chromosome Location : | 6q21 |
MIM : | 137025 |
Pathway : | Adherens junction; Axon guidance; Fc epsilon RI signaling pathway; Focal adhesion; Natural killer cell mediated cytotoxicity; Pathogenic Escherichia coli infection; Prion diseases; T cell receptor signaling pathway |
Function : | non-membrane spanning protein tyrosine kinase activity; ATP binding; glycoprotein binding; identical protein binding; manganese ion binding; metal ion binding; nucleotide binding; transferase activity; tubulin binding |
Products Types
◆ Recombinant Protein | ||
FYN-420H | Recombinant Human FYN Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
FYN-3407M | Recombinant Mouse FYN Protein, His (Fc)-Avi-tagged | +Inquiry |
FYN-2083R | Recombinant Rat FYN Protein, His (Fc)-Avi-tagged | +Inquiry |
FYN-4586H | Recombinant Human FYN Protein, GST-tagged | +Inquiry |
FYN-4585H | Active Recombinant Human FYN Protein, GST/His-tagged | +Inquiry |
◆ Lysates | ||
FYN-6091HCL | Recombinant Human FYN 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFYN protein is involved in regulating synaptic plasticity, which plays a crucial role in learning and memory.
Yes, FYN protein is also associated with cancer, particularly in regulating cell proliferation and survival.
Targeting FYN protein is being studied for its potential applications in the treatment of autoimmune diseases to modulate immune responses.
Some targeted therapies aimed at inhibiting FYN protein have been explored for specific types of cancer.
Yes, FYN protein levels can be measured in clinical settings through various laboratory techniques.
Customer Reviews (3)
Write a reviewthe manufacturer fosters scientific collaboration and knowledge sharing among researchers.
They can offer insights into interpreting results and assist in identifying trends or patterns that may be relevant to the specific research question.
This guarantees a continuous and uninterrupted availability of the protein for researchers, eliminating concerns about potential shortages or delays.
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