Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, J
Cat.No. : | PTPRJ-205H |
Product Overview : | Recombinant human DEP-1 is expressed inE. coli. It contains the catalytic domain of DEP-1 (residues 1024-1306) and has a molecular weight of 32.9 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPRJ-205H |
Description : | DEP-1 (density-enhanced phosphatase-1), also known as PTP-eta or CD148, is a representative of a unique subfamily of receptor protein tyrosine phosphatases with fibronectin type III-like repeats in the extracellular domain and only one catalytic domain. It is expressed in hematopoietic cells, fibroblasts, and endothelial cells. It has been shown to dephosphorylate PDGF. Human DEP-1 is a receptor protein tyrosine phosphatase containing 1445 amino acids. |
Source : | E.coli. |
Purity : | Greater than 95% as determined by Coomassie-stained SDS-PAGE gel. |
Form : | 25 mM Tris-HCl (pH 8.0), 75 mM NaCl, 0.05% Tween-20, 2 mM EDTA, 1 mM DTT and 50% glycerol. Liquid at -20°C. |
Applications : | Removal of phosphates from target substrates. Useful for the study of enzyme kinetics, regulation and for inhibitors screening. |
Specific Activity : | 204 U/μg. One unit will hydrolyze 1 nmol of p-nitrophenyl phosphate per minute at pH 7.4 and 30°C. Assay buffer: 50 mM HEPES (pH 7.4), 2 mM EDTA, 3 mM DTT, 100 mM NaCl and 50 mM pNPP. |
Stability : | 6 months at -20°C. |
Gene Name : | PTPRJ protein tyrosine phosphatase, receptor type, J [ Homo sapiens ] |
Synonyms : | PTPRJ; protein tyrosine phosphatase, receptor type, J; DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA; receptor-type tyrosine-protein phosphatase eta; DEP-1; R-PTP-J; HPTP eta; CD148 antigen; density-enhanced phosphatase 1; protein-tyrosine phosphatase eta; human density enhanced phosphatase-1; protein-tyrosine phosphatase receptor type J; susceptibility to colon cancer 1, mouse, homolog of; protein tyrosine phosphatase, receptor type, J polypeptide; EC 3.1.3.48 |
Gene ID : | 5795 |
mRNA Refseq : | NM_001098503 |
Protein Refseq : | NP_001091973 |
MIM : | 600925 |
UniProt ID : | Q12913 |
Chromosome Location : | 11p11.2 |
Pathway : | Adherens junction |
Function : | hydrolase activity; protein binding; transmembrane receptor protein tyrosine phosphatase activity |
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◆ Lysates | ||
PTPRJ-2675HCL | Recombinant Human PTPRJ 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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