||Recombinant human IL-17C with His-tag was expressed inInsect cell.MW= 19.793 kDa.
||IL-17C is a member of the IL-17 family, which is comprised of six proteins (IL-17A through IL-17F). IL-17 proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. IL-17C has been reported to stimulate the release of TNF-alpha and IL-1β from the monocytic cell line THP-1. IL-17C shares 15% to 30% amino acid sequence identity with the other IL-17 family members. Mouse and human IL-17C share 83% amino acid sequence identity. Human IL-17C cDNA encodes a 197 amino acid protein with a putative 18 amino acid signal peptide. The recombinant human IL-17C is a disulfide-linked homodimer composed of a 19.8 kDa monomeric subunit.
||For best recovery, quick-spin vial prior to opening. Use in a sterile environment.
||Greater than 98% as determined by SDS-PAGE.
||Less than 0.01 ng/ug cytokine as determined by the LAL assay.
||Testing in progress.
||20 mM Phosphate, 0.2 M NaCl, pH 6.0, with 1.0% BSA.
||Store at less than or equal to –70°C.