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Recombinant Human EPH Receptor A7, GST-tagged

Cat.No. : EPHA7-697H
Product Overview : Recombinant human EPH receptor A7 catalytic domain (aa 579-998) with a GST tag is expressed inInsect cells. Activated in vitro via auto-phosphorylation.
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  • Gene Information
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Cat. No. : EPHA7-697H
Description : Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Source : Insect cells.
Concentration : 0.33 mg/ml.
Molecular Weight : 76.7 kDa.
Formulation : Liquid in 50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2mM DTT + 50% glycerol.
Specific Activity : 110 nmole of phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2 μg/ml.
Storage : Stable for 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
Gene Name : EPHA7 EPH receptor A7 [ Homo sapiens ]
Synonyms :
EPHA7; EPH receptor A7; EHK-3; EK11; EPH homology kinase 3; EPH-like kinase 11; Eph homology kinase-3; ephrin type-A receptor 7; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EHK3; EC 2.7.10.1
Gene ID : 2045
mRNA Refseq : NM_004440
Protein Refseq : NP_004431
MIM : 602190
UniProt ID : Q15375
Chromosome Location : 6q16.1
Pathway : Axon guidance
Function : ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane-ephrin receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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