"Hmgb1" Related Products

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Recombinant Mouse Hmgb1 protein, His-tagged

Cat.No. : Hmgb1-2628M
Product Overview : Recombinant Mouse Hmgb1(Met1-Glu215) fused with His tag at N-terminal was expressed in E. coli.
Source : E. coli
Species : Mouse
Tag : His
Form : Sterile liquid; 20 mM Tris-HCl, pH 8.0, 0.2 M NaCl, 1 mM DTT. 0.22 um filtered.
Bio-activity : The ED50 of this protein, as measured by mouse TNF alpha induction in RAW264.7 cells, is 3-25 ug/mL in the presence of 10 ug/mL Polymyxin B. This corresponds to a specific activity of 3,300-40 Units/mg.
Molecular Mass : Has a predicted molecular mass of 27.6 kDa.
Endotoxin : Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Purity : > 98%, as determined by SDS-PAGE
Storage : Store at less than or equal to -70 centigrade.
Concentration : 0.5 mg/mL
Gene Name : Hmgb1 high mobility group box 1 [ Mus musculus ]
Official Symbol : Hmgb1
Synonyms : HMGB1; high mobility group box 1; high mobility group protein B1; high mobility group protein 1; DEF; p30; Hmg1; HMG-1; SBP-1; amphoterin; MGC103168; MGC103169; MGC117896; MGC117897;
Gene ID : 15289
mRNA Refseq : NM_010439
Protein Refseq : NP_034569
MIM :
UniProt ID : P63158
Chromosome Location : 5 G3; 5 89.18 Cm
Pathway : Activated TLR4 signalling, organism-specific biosystem; Activation of DNA fragmentation factor, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Base excision repair, organism-specific biosystem;
Function : 5S rRNA binding; DNA binding; DNA binding, bending; RAGE receptor binding; bent DNA binding; binding; calcium-dependent protein kinase regulator activity; crossed form four-way junction DNA binding; cytokine activity; cytokine activity; double-stranded DNA binding; four-way junction DNA binding; glycolipid binding; heparin binding; open form four-way junction DNA binding; peptide binding;

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