Recombinant Human CDK1, GST-His

• Cat.No.: CDK1-2660H
• Product Overview: Recombinant Human CDK1 (amino acids M1 - M297) both N-terminally fused to GST-HIS6-Thrombin cleavage site is expressed inSf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST&His
• Protein Length: 1-297 a.a.
• Description: CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes.
• Concentration: 0.105 mg/ml.
• Molecular Weight: 77.1 kDa.
• Formulation: Liquid in 50 mM Tris-HCl, pH 8.0 + 100 mM NaCl + 5 mM DTT + 15 mM reduced glutathione + 20% glycerol.
• Specific Activity: 51 pmol/μg x min.

Gene Information

• Gene Name: CDK1 cyclin-dependent kinase 1 [ Homo sapiens ]
• Synonyms:
  CDK1; cyclin-dependent kinase 1; CDC2; CDC28A; P34CDC2; MGC111195; DKFZp686L20222; cell division cycle 2; OTTHUMP00000019659; OTTHUMP00000019660; OTTHUMP00000019661; p34 protein kinase; cell cycle controller CDC2; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; EC 2.7.11.23; EC 2.7.11.22; CCNA2; cyclin A2; CCN1; CCNA; Cyclin-A; Cyclin-A2
• Gene ID: 983
• mRNA Refseq: NM_001170406
• Protein Refseq: NP_001163877
• MIM: 116940
• UniProt ID: P06493
• Chromosome Location: 10q21.1
• Pathway: Cell cycle; Gap junction; Progesterone-mediated oocyte maturation; p53 signaling pathway; Cell cycle; Progesterone-mediated oocyte maturation
• Function: ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; transferase activity; protein binding