"INHA" Related Products


Recombinant Human Inhibin, Alpha, T7-tagged

Cat. No. : INHA-2931H
Product Overview : Recombinant Human INHA was produced inE.coliwith a T7 tag at N-terminus. MW = 39670 Da (19-366 aa).
Description : The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Source : E.coli.
Form : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity : 95%.
Applications : MS. SDS.
Gene Name : INHA inhibin, alpha [ Homo sapiens ]
Synonyms : INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit
Gene ID : 3623
mRNA Refseq : NM_002191
Protein Refseq : NP_002182
MIM : 147380
UniProt ID : P05111
Chromosome Location : 2q33-q36
Function : cytokine activity; growth factor activity; hormone activity; inhibin beta-A binding; protein binding; contributes_to protein binding; protein heterodimerization activity; receptor binding; signal transducer activity

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