"INHA" Related Products

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Recombinant Human Inhibin, Alpha, T7-tagged

Cat. No.: INHA-2931H
Product Overview: Recombinant Human INHA was produced inE.coliwith a T7 tag at N-terminus. MW = 39670 Da (19-366 aa).
Description: The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
Source: E.coli.
Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity: 95%.
Applications: MS. SDS.
Gene Name: INHA inhibin, alpha [ Homo sapiens ]
Synonyms: INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit
Gene ID: 3623
mRNA Refseq: NM_002191
Protein Refseq: NP_002182
MIM: 147380
UniProt ID: P05111
Chromosome Location: 2q33-q36
Function: cytokine activity; growth factor activity; hormone activity; inhibin beta-A binding; protein binding; contributes_to protein binding; protein heterodimerization activity; receptor binding; signal transducer activity

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