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                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human HACL1, T7-tagged

Cat.No. : HACL1-2960H
Product Overview : Recombinant Human HACL1 (1-578 aa) is expressed inE.Coliwith a T7 tag at N-terminus.
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Cat. No. : HACL1-2960H
Description : By analyzing 1,780,295 5"-end sequences of human full-length cDNAs derived from 164 kinds of oligo-cap cDNA libraries, we identified 269,774 independent positions of transcriptional start sites (TSSs) for 14,628 human RefSeq genes. These TSSs were clustered into 30,964 clusters that were separated from each other by more than 500 bp and thus are very likely to constitute mutually distinct alternative promoters. To our surprise, at least 7674 (52%) human RefSeq genes were subject to regulation by putative alternative promoters (PAPs). On average, there were 3.1 PAPs per gene, with the composition of one CpG-island-containing promoter per 2.6 CpG-less promoters.
Source : E.Coli.
MW : 12499 Da.
Purity : 95%.
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
Application : MS. SDS.
Gene Name : HACL1 2-hydroxyacyl-CoA lyase 1 [ Homo sapiens ]
Synonyms : HACL1; 2-hydroxyacyl-CoA lyase 1;HSPC279; 2-HPCL; FLJ55041, HPCL; HPCL2, PHYH2; 1600020H07Rik; 2-hydroxyphytanol-CoA lyase; 2-hydroxyphytanoyl-CoA lyase; phytanoyl-CoA 2-hydroxylase 2; phytanoyl-CoA hydroxylase 2; EC 4.1.-.-
Gene ID : 26061
mRNA Refseq : NM_012260
Protein Refseq : NP_036392
MIM : 604300
UniProt ID : Q9UJ83
Chromosome Location : 3p25.1
Pathway : Peroxisome; Metabolism of lipids and lipoproteins
Function : carbon-carbon lyase activity; identical protein binding; magnesium ion binding; thiamin pyrophosphate binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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