Recombinant Human Uridine-cytidine Kinase 2, His-tagged

• Cat.No.: UCK2-930H
• Product Overview: Recombinant human UCK2 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 30.3kDa (269aa).

Specification

• Cat. No.: UCK2-930H
• Description: UCK2 also known as uridine-cytidine kinase 2 is belongs to the uridinekinase family. UCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. It plays a role in the production of pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B.
• Source: E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF, 1mM EDTA.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQ KQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRL SRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK RQASESSSRP HLEHHHHHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Drug metabolism - other enzymes; Metabolic pathways; Pyrimidine metabolism; Metabolism of nucleotides

Gene Information

• Gene Name: UCK2 uridine-cytidine kinase 2 [ Homo sapiens ]
• Synonyms: uridine-cytidine kinase 2; UK; UMPK; TSA903; UCK2; uridine kinase; uridine monophosphokinase 2; cytidine monophosphokinase 2; uridine monophosphate kinase; testis-specific protein TSA903; Uridine monophosphokinase 2; Cytidine monophosphokinase 2; Testis-specific protein TSA903; EC 2.7.1.48
• Gene ID: 7371
• mRNA Refseq: NM_012474
• Protein Refseq: NP_036606
• MIM: 609329
• UniProt ID: Q9BZX2
• Chromosome Location: 1q23
• Function: ATP binding; kinase activity; molecular_function; nucleotide binding; phosphotransferase activity, alcohol group as acceptor; transferase activity; uridine kinase activity