Recombinant Human Arachidonate 5-lipoxygenase 1
Cat.No. : | ALOX5-723H |
- Specification
- Gene Information
- Related Products
Cat. No. : | ALOX5-723H |
Description : | Recombinant human 5-Lipoxygenase expressed inS. fruigiperdainsect cells using a baculovirus overexpression system. It is localized in the cytosol of resting neutrophils, and is found in the nucleus in rat basophilic leukemia cells and human alveolar macrophages. Upon stimulation of the cell, 5-LO translocates to the nuclear membrane where it is found in association with 5-LO activating protein (FLAP) and with the 85 kDa cPLA2. |
Source : | S. fruigiperda. |
Molar Mass : | 78000. |
Specific Activity : | ~20 units/mg. |
Unit Definition : | One unit is defined as the amount of enzyme that consumes 1.0 nmol of oxygen per min at 25°C in 50 mM Tris-HCl, 100 µM arachidonate, 2 mM CaCl2, 1 mM ATP, 250 µM oxygen. Oxygen consumption can be measured using a oxygraph equipped with a Clark oxygen electrode. |
Form : | Liquid In 100 mM Tris containing 5 mM EGTA, pH 8.0. |
Toxicity : | Standard Handling (MSDS available upon request). |
Storage : | ≤-70°C. Avoid freeze/thaw Following initial thaw, aliquot and freeze (-70°C). |
Gene Name : | ALOX5 arachidonate 5-lipoxygenase [ Homo sapiens ] |
Synonyms : | arachidonate 5-lipoxygenase; ALOX5; 5-LO; 5LPG; LOG5; 5-LOX; MGC163204; leukotriene A4 synthase; arachidonic acid 5-lipoxygenase |
Gene ID : | 240 |
mRNA Refseq : | NM_000698 |
Protein Refseq : | NP_000689 |
MIM : | 152390 |
UniProt ID : | P09917 |
Chromosome Location : | 8p12 |
Pathway : | Arachidonic acid metabolism; Metabolic pathwaysy |
Function : | arachidonate 5-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
ALOX5-120H | Recombinant Human ALOX5 Protein, His-tagged | +Inquiry |
ALOX5-294R | Recombinant Rat ALOX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX5-483M | Recombinant Mouse ALOX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALOX5-053H | Recombinant Human ALOX5 Protein | +Inquiry |
ALOX5-64H | Recombinant Human ALOX5 Protein | +Inquiry |
◆ Lysates | ||
ALOX5-8896HCL | Recombinant Human ALOX5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket