"Adipoq" Related Products

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Recombinant Rat Adipoq, FLAG-tagged

Cat. No.: Adipoq-195R
Product Overview: Recombinant rat adiponectin encoding the mature peptide of rat adiponectin (amino acid His16~Asn244) was tagged with FLAG at the N-terminus. The tagged protein was expressed in a human embryonic kidney cell line,HEK293,and purified from conditioned media.
Description: Adiponectin, also known as apM1, Acrp30, GBP28 and adipoQ, is a circulating hormone predominantly produced from adipose tissue. Many pharmacological studies demonstrated that this protein possesses potent anti-diabetic, anti-atherogenic and anti-inflammatory functions. Supplement of adiponectin protein can decrease blood glucose, improve insulin sensitivity, alleviate fatty liver and prevent atherosclerosis. The protein is post-translationally modified by hydroxylation and glycosylation, and forms three different oligomeric complexes in the circulation.
Source: HEK293.
Formulation: 0.2 m filtered solution in phosphate-buffered saline.
Activity: effect on the phosphorylation of acetyl-CoA carboxylase in C2C12 cells.
Purity: >95%, as determined by SDS-PAGE.
Endotoxin Level: <0.1EU/g, as determined by the LAL method.
Stability Storage And Handling: The protein solution should be stored in working aliquots at -20°C for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Gene Name: Adipoq adiponectin, C1Q and collagen domain containing [ Rattus norvegicus ]
Synonyms: adiponectin, C1Q and collagen domain containing; Acdc; Acrp30; Adipoq; adiponectin; adipocyte complement related protein of 30 kDa
Gene ID: 246253
mRNA Refseq: NM_144744
Protein Refseq: NP_653345
Chromosome Location: 11q23
Pathway: Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus
Function: eukaryotic cell surface binding; hormone activity; molecular_function; protein homodimerization activity

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