"CDKN3" Related Products

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Recombinant Human Cyclin-Dependent Kinase Inhibitor 3, His-tagged

Cat. No. : CDKN3-942H
Product Overview : Recombinant human CDKN3 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 25.9 kDa (232aa).
Description : Cyclin-dependent kinase inhibitor 3, also known CDKN3, belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. Also CDKN3 is important in cell cycle regulation.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.1M NaCl.
Purity : > 90% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKSC GIQDIFVFCT RGELSKYRVP NLLDLYQQCG IITHHHPIAD GGTPDIASCC EIMEELTTCL KNYRKTLIHC YGGLGRSCLV AACLLLYLSD TISPEQAIDS LRDLRGSGAI QTIKQYNYLH EFRDKLAAHL SSRDSQSRSV SR.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : CDKN3 cyclin-dependent kinase inhibitor 3 [ Homo sapiens ]
Synonyms : cyclin-dependent kinase inhibitor 3; KAP; CDI1; CIP2; KAP1; FLJ25787; MGC70625; CDKN3; kinase-associated phosphatase; Cdk-associated protein phosphatase; cyclin-dependent kinase interactor 1; CDK2-associated dual specificity phosphatase; cyclin-dependent kinase interacting protein 2; EC 3.1.3.48,EC 3.1.3.16; CDK2-associated dual-specificity phosphatase; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; Kinase-associated phosphatase
Gene ID : 1033
mRNA Refseq : NM_001130851
Protein Refseq : NP_001124323
MIM : 157680
UniProt ID : Q16667
Chromosome Location : 14q22
Function : hydrolase activity; protein binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity

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