Recombinant Human ICAM2 protein, His-tagged
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|Product Overview :||Recombinant Human ICAM2 (Ser22-Gln223) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).|
|Description :||Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2/CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.|
|Predicted N Terminal :||Ser22|
|Form :||Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.|
|Molecular Mass :||The protein has a calculated MW of 23.3 kDa. The protein migrates as 40-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||Ser22-Gln223|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>95% as determined by SDS-PAGE.|
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
|SDS-PAGE of ICAM2-3163H :||
Human ICAM-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
|Gene Name :||ICAM2|
|Official Symbol :||ICAM2|
|Synonyms :||ICAM2; intercellular adhesion molecule 2; CD102; ICAM-2|
|Gene ID :||3384|
|mRNA Refseq :||NM_000873|
|Protein Refseq :||NP_000864|
|UniProt ID :||P13598|
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