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Recombinant Human IGF2, 25-91 aa

Cat.No. : IGF2-486H
Product Overview : Recombinant human IGF2 was expressed inE.coliand purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW = 7.6 kDa (68aa).
  • Specification
  • Gene Information
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Cat. No. : IGF2-486H
Description : IGF2, as known as insulin-like growth factor 2, is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. This protein is a fetal growth factor, influenced by placental lactogen and abundantly expressed by placental trophoblasts.
Source : E.coli.
Form : Liquid. In phosphate-buffered saline ( pH 7.4) containing 10% glycerol.
Purity : > 90% by SDS - PAGE.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MAYRPSETLC GGELVDTLQF VCGDRGFYFS RPASRVSRRS RGIVEECCFR SCDLALLETY CATPAKSE.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Diabetes pathways
Gene Name : IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ]
Synonyms : insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018
Gene ID : 3481
mRNA Refseq : NM_000612
Protein Refseq : NP_000603
MIM : 147470
UniProt ID : P01344
Chromosome Location : 11p15.5
Function : growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can IGF2 be used as a predictive marker for certain diseases? 11/12/2021

Yes, IGF2 levels may serve as predictive markers for certain diseases. Monitoring its expression could help identify individuals at risk or track disease progression.

How can IGF2 be targeted for therapeutic interventions? 04/20/2021

Researchers are exploring various approaches, including drug development, to modulate IGF2 levels for therapeutic purposes. This may involve targeting its receptors or modifying its expression.

How does IGF2 relate to aging and age-related diseases? 12/28/2020

IGF2 has been linked to the aging process and age-related diseases. Exploring its role may provide insights into slowing down aging or managing age-related conditions.

Are there therapeutic applications of IGF2 in regenerative medicine? 12/08/2020

Research is exploring the potential use of IGF2 in regenerative medicine due to its role in cell growth and tissue repair. It may offer new avenues for tissue regeneration.

Are there clinical trials exploring IGF2 as a therapeutic target? 05/21/2019

Yes, there are ongoing clinical trials investigating the use of IGF2 in various conditions. These trials aim to assess its safety and efficacy in a clinical setting.

Customer Reviews (3)

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Reviews
01/24/2023

    The IGF2 protein is an exceptional choice that meets the highest standards of quality, making it perfectly suited for your experimental needs.

    01/26/2019

      The IGF2 protein is of the highest quality and perfectly suited for your experimental requirements.

      01/20/2019

        In addition to its exceptional quality, the IGF2 protein is backed by excellent technical support offered by the manufacturer.

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