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Recombinant Human IGF2 protein, His & T7-tagged

Cat.No. : IGF2-816H
Product Overview : Recombinant Human IGF2 aa. (Ala25~Glu91 (Accession # P01344)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 11.3kDa
Protein length : Ala25~Glu91 (Accession # P01344)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 7.7.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name : IGF2 insulin like growth factor 2 [ Homo sapiens (human) ]
Official Symbol : IGF2
Synonyms : IGF2; insulin like growth factor 2; GRDF; IGF-II; PP9974; C11orf43; insulin-like growth factor II; T3M-11-derived growth factor; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor type 2; preptin
Gene ID : 3481
mRNA Refseq : NM_000612.5
Protein Refseq : NP_000603.1
UniProt ID : P01344

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can IGF2 be used as a predictive marker for certain diseases? 11/12/2021

Yes, IGF2 levels may serve as predictive markers for certain diseases. Monitoring its expression could help identify individuals at risk or track disease progression.

How can IGF2 be targeted for therapeutic interventions? 04/20/2021

Researchers are exploring various approaches, including drug development, to modulate IGF2 levels for therapeutic purposes. This may involve targeting its receptors or modifying its expression.

How does IGF2 relate to aging and age-related diseases? 12/28/2020

IGF2 has been linked to the aging process and age-related diseases. Exploring its role may provide insights into slowing down aging or managing age-related conditions.

Are there therapeutic applications of IGF2 in regenerative medicine? 12/08/2020

Research is exploring the potential use of IGF2 in regenerative medicine due to its role in cell growth and tissue repair. It may offer new avenues for tissue regeneration.

Are there clinical trials exploring IGF2 as a therapeutic target? 05/21/2019

Yes, there are ongoing clinical trials investigating the use of IGF2 in various conditions. These trials aim to assess its safety and efficacy in a clinical setting.

Customer Reviews (3)

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Reviews
01/24/2023

    The IGF2 protein is an exceptional choice that meets the highest standards of quality, making it perfectly suited for your experimental needs.

    01/26/2019

      The IGF2 protein is of the highest quality and perfectly suited for your experimental requirements.

      01/20/2019

        In addition to its exceptional quality, the IGF2 protein is backed by excellent technical support offered by the manufacturer.

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