"LSM4" Related Products

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Recombinant Human LSM4, His-tagged

Cat. No. : LSM4-3398H
Product Overview : Recombinant human LSM4 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 17.5 kDa (159aa).
Description : LSM4, also called U6 snRNA-associated Sm-like protein or glycine-rich protein (GRP), forms donut-shaped heptameric complexes that are involved in various steps of RNA metabolism. It facilitates RNA protein interactions and structural changes that are required during ribosomal subunit assembly. It binds specifically to the 3"-terminal U-tract of U6 snRNA.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT.
Purity : > 90% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MLPLSLLKTA QNHPMLVELK NGETYNGHLV SCDNWMNINL REVICTSRDG DKFWRMPECY IRGSTIKYLR IPDEIIDMVK EEVVAKGRGR GGLQQQKQQK GRGMGGAGRG VFGGRGRGGI PGTGRGQPEK KPGRQAGKQ.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : RNA degradation; Spliceosome; Metabolism of RNA
Gene Name : LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) [ Homo sapiens ]
Synonyms : LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); YER112W; LSM4; U6 snRNA-associated Sm-like protein LSm4; GRP; glycine-rich protein;Glycine-rich protein
Gene ID : 25804
mRNA Refseq : NM_012321
Protein Refseq : NP_036453
MIM : 607284
UniProt ID : Q9Y4Z0
Chromosome Location : 19p13.11
Function : RNA binding; protein binding

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