"POLR2L" Related Products

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Recombinant Human POLR2L, His-tagged

Cat. No. : POLR2L-3056H
Product Overview : Recombinant HumanPOLR2L (1-67 aa) is expressed inE.Coliwith a His tag at N-terminus.
Description : POLR2L is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Source : E.Coli.
MW : 7645 Da.
Purity : 95%.
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
Application : MS. SDS.
Gene Name : POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa [ Homo sapiens ]
Synonyms : POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; RBP10; RPB10; RPABC5; RPB7.6; hRPB7.6; hsRPB10b; RPB10beta; DNA directed RNA polymerase II polypeptide L; EC 2.7.7.6
Gene ID : 5441
mRNA Refseq : NM_021128
Protein Refseq : NP_066951
MIM : 601189
UniProt ID : P62875
Chromosome Location : 11p15
Pathway : Huntington"s disease; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Gene Expression; HIV Infection; Regulatory RNA pathways; Transcription; mRNA Processing
Function : DNA binding; DNA-directed RNA polymerase activity; metal ion binding; protein kinase activity; zinc ion binding

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