Recombinant Human Activin A
Cat.No. : | INHBA-2884H |
Product Overview : | Human Activin A produced in Insect cells is a 26 kDa disulfide-linked homodimer of two beta A chains, each containing 116 amino acid residues. |
- Specification
- Gene Information
- Related Products
Cat. No. : | INHBA-2884H |
Description : | Activin A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, Follistatin. |
Source : | Insect cells. |
Form : | Lyophilized. |
Purity : | > 95% by SDS-PAGE and HPLC analyses. |
Endotoxin Level : | < 0.1 ng per μg of Activin A. |
Biological Activity : | The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is < 2 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. |
Reconstitution : | The human Activin A should be reconstituted in water to a concentration of 0.5 mg/ml. This solution can be stored at 4°C for 1 month or -20°C for future use. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at -20°C. |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Human Activin A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | INHBA inhibin, beta A [ Homo sapiens ] |
Synonyms : | INHBA; inhibin, beta A; EDF; FRP; Inhibin, beta-1; OTTHUMP00000207260; FSH-releasing protein; erythroid differentiation factor; follicle-stimulating hormone-releasing protein; inhibin, beta A (activin A, activin AB alpha polypeptide); Activin beta-A chain; Erythroid differentiation protein; FSH-releasing protein |
Gene ID : | 3624 |
mRNA Refseq : | NM_002192 |
Protein Refseq : | NP_002183 |
MIM : | 147290 |
UniProt ID : | P08476 |
Chromosome Location : | 7p15-p13 |
Pathway : | Cytokine-cytokine receptor interaction; TGF-beta signaling pathway |
Function : | cytokine activity; follistatin binding; growth factor activity; hormone activity; identical protein binding; protein heterodimerization activity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
INHBA-196H | Active Recombinant Human/Mouse/Rat INHBA Protein | +Inquiry |
INHBA-552H | Recombinant Human INHBA Protein | +Inquiry |
INHBA-220H | Recombinant Active Human INHBA Protein, His-tagged(C-ter) | +Inquiry |
INHBA-2404H | Recombinant Human INHBA Protein, MYC/DDK-tagged | +Inquiry |
INHBA-5120H | Recombinant Human INHBA Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
INHBA-2078MCL | Recombinant Mouse INHBA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket