|Product Overview:||Recombinant Human NAT6 was produced in E.coli with a T7 tag at N-terminus. MW = 31445 Da (1-286 aa).|
|Description:||N-acetyltransferase, also known as FUS2 (NAT6), is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to acrylamines. This enzyme is physically localized in the cytoplasm and its activity has been documented by its feasibility to acetylate the N-terminus of proteins using a ping-pong-like mechanism and by its substrate specificity. Since the Fus-2 gene maps to the chromosomal region 3p21.3, which contains at least one tumor suppressor gene, the N-acetyltransferase functions of Fus-2 may be relevant to its potential role in cancer.|
|Form:||10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.|
|Gene Name:||NAT6 N-acetyltransferase 6 (GCN5-related) [ Homo sapiens ]|
|Synonyms:||NAT6; N-acetyltransferase 6 (GCN5-related); EC 2.3.1.-; FUS-2; FUS2; N-acetyltransferase 6; Protein fus-2; Protein fusion-2; putative tumor suppressor|
|Pathway:||1- and 2-Methylnaphthalene degradation; Alkaloid biosynthesis II; Benzoate degradation via CoA ligation; Ethylbenzene degradation; Glycerophospholipid metabolism; Limonene and pinene degradation; Phenylalanine metabolism; Tyrosine metabolism|
|Function:||N-acetyltransferase activity; acyltransferase activity; transferase activity|
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