Recombinant Human PHGDH, T7-tagged

• Cat.No.: PHGDH-851H
• Product Overview: Recombinant Human PHGDH (1-533aa) is expressed in E.Coli with a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-533 a.a.
• Description: 3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
• MW: 56519 Da.
• Purity: 95%.
• Formulation: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: PHGDH phosphoglycerate dehydrogenase [ Homo sapiens ]
• Synonyms: PHGDH; phosphoglycerate dehydrogenase; RP4-683H9.1, 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA; 3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95
• Gene ID: 26227
• mRNA Refseq: NM_006623
• Protein Refseq: NP_006614
• MIM: 606879
• UniProt ID: O43175
• Chromosome Location: 1p12
• Pathway: Glycine, serine and threonine metabolism; Metabolic pathways
• Function: NAD or NADH binding; cofactor binding; electron carrier activity; phosphoglycerate dehydrogenase activity