Recombinant Human PHGDH, T7-tagged


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Recombinant Human PHGDH, T7-tagged

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Cat. No. : PHGDH-851H
Product Overview : Recombinant Human PHGDH (1-533aa) is expressed in E.Coli with a T7 tag at N-terminus.
Description : 3-Phosphoglycerate dehydrogenase (PHGDH; EC catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
Source : E.Coli.
MW : 56519 Da.
Purity : 95%.
Formulation : 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
Application : MS. SDS.
PDB rendering based on 2g76. :

Gene Name : PHGDH phosphoglycerate dehydrogenase [ Homo sapiens ]
Synonyms : PHGDH; phosphoglycerate dehydrogenase; RP4-683H9.1, 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA; 3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; EC
Gene ID : 26227
mRNA Refseq : NM_006623
Protein Refseq : NP_006614
MIM : 606879
UniProt ID : O43175
Chromosome Location : 1p12
Pathway : Glycine, serine and threonine metabolism; Metabolic pathways
Function : NAD or NADH binding; cofactor binding; electron carrier activity; phosphoglycerate dehydrogenase activity

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