"DUSP14" Related Products

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Recombinant Human DUSP14, T7-tagged

Cat. No. : DUSP14-853H
Product Overview : Recombinant Human DUSP14 (1-198 aa) is expressed in E.Coli with a T7 tag at N-terminus.
Description : Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009.
Source : E.Coli.
MW : 22255 Da.
Purity : 95%.
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
Application : MS. SDS.
Gene Name : DUSP14 dual specificity phosphatase 14 [ Homo sapiens ]
Synonyms : DUSP14; dual specificity phosphatase 14; MKP-L, MKP6; MAP kinase phosphatase 6; MKP-1 like protein tyrosine phosphatase; MKP-1-like protein tyrosine phosphatase; MKP-6; OTTHUMP00000164064; OTTHUMP00000164065; dual specificity protein phosphatase 14; mitogen-activated protein kinase phosphatase 6; EC 3.1.3.16; EC 3.1.3.48
Gene ID : 11072
mRNA Refseq : NM_007026
Protein Refseq : NP_008957
MIM : 606618
UniProt ID : O95147
Chromosome Location : 17q12
Pathway : MAPK signaling pathway
Function : MAP kinase tyrosine/serine/threonine phosphatase activity; hydrolase activity; protein tyrosine phosphatase activity

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