Recombinant Human DUSP14, T7-tagged

• Cat.No.: DUSP14-853H
• Product Overview: Recombinant Human DUSP14 (1-198 aa) is expressed in E.Coli with a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-198 a.a.
• Description: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009.
• MW: 22255 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
• Application: MS. SDS.

Gene Information

• Gene Name: DUSP14 dual specificity phosphatase 14 [ Homo sapiens ]
• Synonyms: DUSP14; dual specificity phosphatase 14; MKP-L, MKP6; MAP kinase phosphatase 6; MKP-1 like protein tyrosine phosphatase; MKP-1-like protein tyrosine phosphatase; MKP-6; OTTHUMP00000164064; OTTHUMP00000164065; dual specificity protein phosphatase 14; mitogen-activated protein kinase phosphatase 6; EC 3.1.3.16; EC 3.1.3.48
• Gene ID: 11072
• mRNA Refseq: NM_007026
• Protein Refseq: NP_008957
• MIM: 606618
• UniProt ID: O95147
• Chromosome Location: 17q12
• Pathway: MAPK signaling pathway
• Function: MAP kinase tyrosine/serine/threonine phosphatase activity; hydrolase activity; protein tyrosine phosphatase activity