Recombinant Human TGFBR1, GST-His
Cat.No. : | TGFBR1-716H |
Product Overview : | Recombinant Human TGFB-R1, C-terminal fragment, amino acids T200-M503, N-terminal GST-HIS6 fusion protein with a Thrombin cleavage site, was expressed inSf9insect cells.MW = 64,168 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TGFBR1-716H |
Description : | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). |
Source : | Baculovirus infected Sf9 cells. |
Purification : | GST-Affinity Chromatography. |
Product Identity : | TGFB-R1 was confirmed as TGFB-R1 by mass spectroscopy LCESI-MS/MS. |
Storage Buffer : | 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol. |
Concentration : | 0.193 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein). |
Specific Activity : | 501 pmol/μg×min. |
Storage : | -80°C. Avoid repeated freeze-thaw cycles! |
Gene Name : | TGFBR1 transforming growth factor, beta receptor 1 [ Homo sapiens ] |
Synonyms : | TGFBR1; transforming growth factor, beta receptor 1; AAT5; ALK5; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4; 9q22; activin receptor-like kinase 5; transforming growth factor beta receptor I; serine/threonine-protein kinase receptor R4; activin A receptor type II-like kinase, 53Kd; activin A receptor type II-like kinase, 53kDa; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD); EC 2.7.11.30; TGF-beta receptor type-1; Transforming growth factor-beta receptor type I; TGF-beta receptor type I; TGF-beta type I receptor; TbetaR-I; OTTHUMP00000021783 |
Gene ID : | 7046 |
mRNA Refseq : | NM_001130916 |
Protein Refseq : | NP_001124388 |
MIM : | 190181 |
UniProt ID : | P36897 |
Chromosome Location : | 9q22 |
Pathway : | Adherens junction; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Endocytosis; MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; TGF-beta signaling pathway |
Function : | ATP binding; SMAD binding; magnesium ion binding; manganese ion binding; nucleotide binding; protein complex binding; protein heterodimerization activity; protein serine/threonine kinase activity; receptor activity; transferase activity; transforming growth factor beta binding; transforming growth factor beta receptor activity, type I; type II transforming growth factor beta receptor binding; ubiquitin protein ligase binding |
Products Types
◆ Recombinant Protein | ||
TGFBR1-701H | Recombinant Human TGFBR1 Protein, MYC/DDK-tagged | +Inquiry |
TGFBR1-02H | Active Recombinant Human TGFBR1 Protein (27-126aa), C-hIgG-His tagged | +Inquiry |
TGFBR1-143H | Active Recombinant Human TGFBR1 protein(Thr200-Met503), His&GST-tagged | +Inquiry |
TGFBR1-5523H | Recombinant Human Transforming Growth Factor, Beta Receptor 1 | +Inquiry |
TGFBR1-1293H | Recombinant Human TGFBR1 Protein (T200-M503), Tag Free | +Inquiry |
◆ Lysates | ||
TGFBR1-001HCL | Recombinant Human TGFBR1 cell lysate | +Inquiry |
TGFBR1-2482HCL | Recombinant Human TGFBR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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