Recombinant Human Fms-Related Tyrosine Kinase 4, GST-His FLT4-720H

Recombinant Human Fms-Related Tyrosine Kinase 4, GST-His

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Recombinant Human Fms-Related Tyrosine Kinase 4, GST-His

FLT4 Related Products

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Cat. No. : FLT4-720H
Product Overview : Human VEGF-R3, C-terminal fragment, amino acids N799-R1298, activated, N-terminal GSTHIS6 fusion protein with a Thrombin cleavage site, was expressed inSf9insect cells.MW = 85.565 Da.
Description : This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Source : Baculovirus infected Sf9 cells.
Purification : GST-Affinity Chromatography.
Product Identity : VEGF-R3 was confirmed as VEGF-R3 by mass spectroscopy LCESI-MS/MS.
Activation : in vitro autoactivation.
Storage Buffer : 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol.
Concentration : 0.151 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity : 58 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : FLT4 fms-related tyrosine kinase 4 [ Homo sapiens ]
Synonyms : FLT4; fms-related tyrosine kinase 4; PCL; FLT41; LMPH1A; VEGFR3; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; vascular endothelial growth factor receptor 3; EC 2.7.10.1; 3` partial; Tyrosine-protein kinase receptor FLT4; VEGFR-3
Gene ID : 2324
mRNA Refseq : NM_002020
Protein Refseq : NP_002011
MIM : 136352
UniProt ID : P35916
Chromosome Location : 5q34-q35
Pathway : Cytokine-cytokine receptor interaction; Focal adhesion; Signaling by VEGF
Function : ATP binding; growth factor binding; nucleotide binding; receptor activity; transferase activity; vascular endothelial growth factor receptor activity

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