"MAPK8" Related Products

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Recombinant Human Mitogen-activated Protein Kinase 8

Cat. No.: MAPK8-751H
Product Overview: Recombinant Human Human Mitogen-activated Protein Kinase 8 Amino acidsM1-Q384, is expressed inE.coli.
Description: Mitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
Source: E.coli.
Purification: Immobilized Metal Affinity Chromatography.
Product Identity: JNK1 was confirmed as JNK1 by mass spectroscopy LC-ESI-MS/MS.
MW: 44,292 Da.
Storage Buffer: 50 mM Tris-HCl, pH 7.5; 100 mM NaCl, 5 mM DTT, 20% glycerol.
Concentration: 0.513 μg/μl.
Specific Activity: 2514 pmol/μg×min.
Storage: -80°C. Avoid repeated freeze-thaw cycles!
Gene Name: MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Synonyms:
MAPK8; mitogen-activated protein kinase 8; JNK-46; JNK1 alpha protein kinase; JNK1 beta protein kinase; JUN N-terminal kinase; MAP kinase 8; MAPK 8; OTTHUMP00000019552; c-Jun N-terminal kinase 1; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; protein kinase JNK1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; EC 2.7.11.24
Gene ID: 5599
mRNA Refseq: NM_002750
Protein Refseq: NP_002741
MIM: 601158
UniProt ID: P45983
Chromosome Location: 10q11.22
Pathway: Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Focal adhesion; MAPK signaling pathway; NOD-like receptor signaling pathway; Pathways in cancer; Progesterone-mediated oocyte maturation; Type II diabetes mellitus; Wnt signaling pathway
Function: ATP binding;JUN kinase activity; MAP kinase activity; kinase activity; protein serine/threonine kinase activity

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