"IKBKB" Related Products

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Recombinant Human IKBKB, GST-His

Cat. No. : IKBKB-2661H
Product Overview : Recombinant Human IKK-beta, full length, amino acids M1-S756, N-terminal GST-HIS6 fusion protein with a Thrombin cleavage site, expressed inSf9 insect cells.
Description : IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene.
Source : Sf9 insect cells.
Purification : Immobilized Metal Affinity Chromatography.
Product Identity : IKK-beta was confirmed as IKK-beta by mass spectroscopy LCESI-MS/MS.
MW : 120.201 Da.
Storage Buffer : 50 mM Tris-HCl, pH 7.5; 100 mM NaCl, 5 mM DTT, 20% glycerol.
Concentration : 0.695 μg/μl.
Specific Activity : 2 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta [ Homo sapiens ]
Synonyms :
IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-B; inhibitor of nuclear factor kappa-B kinase subunit beta; nuclear factor NF-kappa-B inhibitor kinase beta; IKK2; IKKB; NFKBIKB; FLJ33771; FLJ36218; FLJ38368; FLJ40509; IKK-beta; MGC131801; EC 2.7.11.10
Gene ID : 3551
mRNA Refseq : NM_001190720
Protein Refseq : NP_001177649
MIM : 603258
UniProt ID : O14920
Chromosome Location : 8p11.2
Pathway : Acute myeloid leukemia; Colorectal cancer; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; Progesterone-mediated oocyte maturation; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus
Function : ATP binding; IkappaB kinase activity; identical protein binding; nucleotide binding; protein heterodimerization activity; transcription activator activity; transferase activity

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