Recombinant Human FER, GST-His

• Cat.No.: FER-2706H
• Product Overview: Recombinant Human FER Amino acids M541-T822, N-terminally fused to GST-His6-Thrombin cleavage site. It is expressed in Baculovirus infectedSf9 cells.

Specification

• Cat. No.: FER-2706H
• Description: Proto-oncogene tyrosine-protein kinase FER is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
• Source: Sf9 cells.
• Product Identity: FER was confirmed as FER by mass spectroscopy LC-ESI-MS/MS.
• Purification: GST-Affinity Chromatography.
• MW: 61.733 Da.
• Storage Buffer: 50 mM Tris-HCl, pH 8.0; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
• Concentration: 0.183 μg/μl.
• Specific Activity: 298 pmol/μg×min.
• Storage: -80°C. Avoid repeated freeze-thaw cycles!

Gene Information

• Gene Name: FER fer (fps/fes related) tyrosine kinase [ Homo sapiens ]
• Synonyms:
  FER; fer (fps/fes related) tyrosine kinase; p94-Fer; phosphoprotein NCP94; proto-oncogene c-Fer; tyrosine kinase 3; tyrosine-protein kinase Fer; TYK3; EC 2.7.10.2
• Gene ID: 2241
• mRNA Refseq: NM_005246
• Protein Refseq: NP_005237
• MIM: 176942
• UniProt ID: P16591
• Chromosome Location: 5q21
• Pathway: Adherens junction
• Function: ATP binding; Rab GTPase binding; gamma-catenin binding; non-membrane spanning protein tyrosine kinase activity; protein kinase binding; protein tyrosine kinase activity; transferase activity