Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A)
| Cat.No. : | IGF2-450H |
| Product Overview : | Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A) is expressed inE.coli. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | IGF2-450H |
| Description : | Human Des(1-6) Insulin-like Growth Factor-II (Des(1-6)IGF-II) is a 61 amino acid analog of human IGF-II, lacking the first six N-terminal amino acids. This analog of IGF-II binds to the Type 1 and Type 2 IGF receptors with similar affinity to IGF-II. Human Des(1-6)IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which modulate the actions of IGFs. |
| Source : | E.coli. |
| Molecular Weight : | 6765 daltons – confirmed by Mass Spectrometry. |
| N-terminal Sequence Analysis : | 5 residues > 95 % single sequence. |
| Purity : | > 95 % (by HPLC and N-terminal sequence analysis). |
| Biological Activity : | Type 1 IGF receptor binding assay: ED50 < 50 ng/ml; Type 2 IGF receptor binding assay: ED50 < 100 ng/ml;IGF binding protein assay: ED50 > 1000 ng/ml; Stimulation of protein synthesis in rat L6 myoblasts: ED50 < 75 ng/ml. |
| Endotoxin : | < 0.1 EU/µg. |
| State And Appearance : | Lyophilized white powder. Dried from 0.1 M acetic acid and stored under nitrogen at a slight vacuum. |
| Detection : | Determination of IGF-I or IGF-II in a Range of Species by Radioimmunoassay (RIA). |
| Reconstitution : | Handling of Novozymes GroPep IGF-I, IGF-II and IGF Analogs. |
| Storage/Stability : | At least 2 years at 2 - 4°C (lyophilized). |
| Gene Name : | IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ] |
| Synonyms : | insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018 |
| Gene ID : | 3481 |
| mRNA Refseq : | NM_000612 |
| Protein Refseq : | NP_000603 |
| MIM : | 147470 |
| UniProt ID : | P01344 |
| Chromosome Location : | 11p15.5 |
| Pathway : | Diabetes pathways |
| Function : | growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding |
Products Types
| ◆ Native Protein | ||
| IGF2-621H | Native Human Insulin-Like Growth Factor 2 (somatomedin A) | +Inquiry |
| IGF2-29116TH | Native Human IGF2 | +Inquiry |
| ◆ Lysates | ||
| IGF2-5266HCL | Recombinant Human IGF2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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