"IGF2" Related Products

Expand
Expand
Expand

Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A)

Cat. No. : IGF2-450H
Product Overview : Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A) is expressed inE.coli.
Description : Human Des(1-6) Insulin-like Growth Factor-II (Des(1-6)IGF-II) is a 61 amino acid analog of human IGF-II, lacking the first six N-terminal amino acids. This analog of IGF-II binds to the Type 1 and Type 2 IGF receptors with similar affinity to IGF-II. Human Des(1-6)IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which modulate the actions of IGFs.
Source : E.coli.
Molecular Weight : 6765 daltons – confirmed by Mass Spectrometry.
N-terminal Sequence Analysis : 5 residues > 95 % single sequence.
Purity : > 95 % (by HPLC and N-terminal sequence analysis).
Biological Activity : Type 1 IGF receptor binding assay: ED50 < 50 ng/ml; Type 2 IGF receptor binding assay: ED50 < 100 ng/ml;IGF binding protein assay: ED50 > 1000 ng/ml; Stimulation of protein synthesis in rat L6 myoblasts: ED50 < 75 ng/ml.
Endotoxin : < 0.1 EU/µg.
State And Appearance : Lyophilized white powder. Dried from 0.1 M acetic acid and stored under nitrogen at a slight vacuum.
Detection : Determination of IGF-I or IGF-II in a Range of Species by Radioimmunoassay (RIA).
Reconstitution : Handling of Novozymes GroPep IGF-I, IGF-II and IGF Analogs.
Storage/Stability : At least 2 years at 2 - 4°C (lyophilized).
Gene Name : IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ]
Synonyms : insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018
Gene ID : 3481
mRNA Refseq : NM_000612
Protein Refseq : NP_000603
MIM : 147470
UniProt ID : P01344
Chromosome Location : 11p15.5
Pathway : Diabetes pathways
Function : growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.