"UBE2A" Related Products

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Recombinant Human UBE2A, His-tagged

Cat. No.: UBE2A-53H
Product Overview: Recombinant human UBE2A, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 19.4 kDa (172aa).
Description: Ubiquitin-conjugating enzyme E2 A isoform 1, also known as UBE2A is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA.
Purity: > 95% by SDS - PAGE.
Concentration: 0.5mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTIEFT EEYPNKPPTV RFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWR DC.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: UBE2A ubiquitin-conjugating enzyme E2A (RAD6 homolog) [ Homo sapiens ]
Synonyms: ubiquitin-conjugating enzyme E2A (RAD6 homolog); UBC2; HHR6A; RAD6A; UBE2A; ubiquitin-conjugating enzyme E2 A; HR6A; RAD6 homolog A; ubiquitin-protein ligase A; ubiquitin carrier protein A; Ubiquitin-protein ligase A; Ubiquitin carrier protein A; EC 6.3.2.19; hHR6A
Gene ID: 7319
mRNA Refseq: NM_003336
Protein Refseq: NP_003327
MIM: 312180
UniProt ID: P49459
Chromosome Location: Xq24-q25
Pathway: Ubiquitin mediated proteolysis
Function: ATP binding; ligase activity; nucleotide binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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