"NGF" Related Products


Recombinant Human Nerve Growth Factor (Beta Polypeptide)

Cat. No.: NGF-28H
Description: Beta-NGF, also known as nerve growth factor beta-1, NGF-b1, or NGF-beta, is a neurotrophic factor that influences the growth and differentiation of sympathetic and sensory neurons. Beta-NGF, comprised alpha, beta, and gamma subunits, is a 26 kDa non-covalently associated homodimer with 2 potential N-linked glycosylation sites.
Source: NSO.
Analysis Note: The biological activity is measured in a cell proliferation assay using a factor-dependent human erythroleukemic cell line, TF-1.
Biochem/physiol Actions: NGF-β promotes the survival and cholinergic phenotype of basal forebrain cholinergic neurons and stimulates neurite outgrowth of embryonic trigeminal motor neurons in vitro.
Physical Form: Lyophilized from 0.2% acetic acid containing 5 mg bovine serum albumin.
Assay: >97% (SDS-PAGE).
Form: lyophilized powder.
Potency: 0.15-3.0 ng/mL ED50/EC50.
Total Impurities: endotoxin, tested.
Suitability: cell culture tested.
Storage Temp: −20°C.
Gene Name: NGF nerve growth factor (beta polypeptide) [ Homo sapiens ]
Synonyms: NGF; nerve growth factor (beta polypeptide); NGFB; HSAN5; Beta-NGF; MGC161426; MGC161428; Beta-nerve growth factor; nerve growth factor, beta subunit; nerve growth factor, beta polypeptide; beta-nerve growth factor; OTTHUMP00000013653
Gene ID: 4803
mRNA Refseq: NM_002506
Protein Refseq: NP_002497
MIM: 162030
UniProt ID: P01138
Chromosome Location: 1p13.1
Pathway: Apoptosis; MAPK signaling pathway; Neurotrophin signaling pathway; Signalling by NGF
Function: growth factor activity; rve growth factor receptor binding; receptor signaling protein activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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